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Cancer Clinical Trials

Almost everything we know about how to diagnose and treat cancer today was learned through the participation of people just like you. You can make a difference for future cancer patients by taking part in a clinical trial.

Your provider will discuss whether a clinical trial is available to you. Enrolling is your choice. You may choose to take part or not and are free to leave at any time.

See our open cancer clinical trials below. For more information, including how to enroll, please call 609-677-7735.

To learn more about clinical trials, visit the National Cancer Institute site.

Active Clinical Trials

Brain Cancer | Breast Cancer | Genitourinary Cancer | Gastrointestinal Cancer | Head & Neck Cancer | Multiple Disease Sites | Prostate Cancer

Brain Cancer

CCTG-CE.7

Category
Brain Cancer

Full Name
Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5-15 Brain Metastases

Brief Description
A Phase III Trial of Stereotactic Radiosurgery Compared with Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) plus Memantine for 5 – 15 brain metastases

Sponsor
NCI Sponsored

ClinicalTrials.gov ID NCT03550391

View on Clinical Trials.gov

   

Breast Cancer

S2010

Category
Breast Cancer

Full Name
Monitoring Symptoms to Help Young Women Take Hormone Therapy for Stage I-III Breast Cancer, ASPEN Study

Brief Description
A Randomized Phase III Trial Comparing Active Symptom Monitoring Plus Patient Education Versus Patient Education Alone to Improve Persistence With Endocrine Therapy in Young Women With Stage I-III Breast Cancer (ASPEN)

Sponsor
SWOG Sponsored

ClinicalTrials.gov ID NCT05568472

View on Clinical Trials.gov

S1703

Category
Breast Cancer

Full Name
Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

Brief Description
A randomized trial that studies how well serum tumor marker directed disease monitoring works in monitoring patients with hormone receptor positive Her2 negative breast cancer that has spread to other places in the body.

Sponsor
SWOG Sponsored

ClinicalTrials.gov ID NCT03723928

View on Clinical Trials.gov

A012301

Category
Breast Cancer

Full Name
LoTam: A Randomized, Phase III Clinical Trial of Low-Dose Tamoxifen for Selected Patients With Molecular Low-Risk Early-Stage Breast Cancer

Brief Description
A phase III trial comparing the effect of low dose tamoxifen to usual hormonal therapy in treating post-menopausal women with hormone positive, HER2 negative early stage breast cancer.

Sponsor
SWOG Sponsored

ClinicalTrials.gov ID NCT06671912

View on Clinical Trials.gov

Gastrointestinal Cancer

NRG-GI008

Category
Gastrointestinal Cancer

Full Name
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Brief Description
This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon cancer.

Sponsor
NRG Oncology Sponsored

ClinicalTrials.gov ID NCT05174169

View on Clinical Trials.gov

   

Genitourinary Cancer

A031704

Category
Genitourinary Cancer

Full Name
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

Brief Description
PD-Inhibitor (Nivolumab) & Ipilimumab followed by Nivolumab vs VEGF TKI Cabozantinib with Nivolumab: A Phase III Trial in Metastatic Untreatet Renal Cell Cancer (PDIGREE)

Sponsor
NCI Sponsored

ClinicalTrials.gov ID NCT03793166

View on Clinical Trials.gov

   
EA3161

Category
Head & Neck Cancer

Full Name
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

Brief Description
A Phase II/III Randomized Study of Maintenance Nivolumab versus Observation in Patients with Locally Advanced, Intermediate-Risk HPV Positive Oropharyngeal Cancer

Sponsor
NCI Sponsored

ClinicalTrials.gov ID NCT03811015

View on Clinical Trials.gov

   

Multiple Disease Sites

Research Patient Registry

Category
Multiple Disease Sites

Full Name
RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT

Brief Description
A research registry of the de-identified treatment and follow-up data of patients receiving stereotactic radiosurgery (SRS)/stereotactic body radiation therapy (SBRT), including CyberKnife (CK)

Sponsor
The Radiosurgery Society Sponsored

ClinicalTrials.gov ID NCT01885299

View on Clinical Trials.gov

   

Prostate

MEVPRO-1 (C2321014)

Category
Prostate Cancer

Full Name
A phase III, randomized, open-label study of PF-06821497 (Mevrometostat) in combination with Enzalutamide or Docetaxel for Metastatic Castration Resistant Prostate Cancer previously treated with Abiraterone Acetate.

Brief Description
A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).

Sponsor
Pfizer Sponsored

ClinicalTrials.gov ID NCT06551324

View on Clinical Trials.gov

NRG-GU009

Category
Prostate Cancer

Full Name
Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial

Brief Description
Parallel Phase III Randomized Trials for High Risk Prostate Cancer Evaluating De-Intensification for Lower Genomic Risk and Intensification of Concurrent Therapy for Higher Genomic Risk With Radiation (PREDICT-RT*)

Sponsor
NRG Sponsored

ClinicalTrials.gov ID NCT04513717

View on Clinical Trials.gov

NRG-GU010

Category
Prostate Cancer

Full Name
Two Studies for Patients with Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients with a Low Gene Risk Score and Testing a More Intense Treatment for Patients with a Higher Gene Risk Score.

Brief Description
Parallel Phase III Randomized Trials of Genomic-Risk Stratified Unfavorable Intermediate Risk Prostate Cancer: De-Intensification and Intensification Clinical Trial Evaluation (GUIDANCE)

Sponsor
NRG Sponsored

ClinicalTrials.gov ID NCT05050084

View on Clinical Trials.gov

OPTYX Registry

Category
Prostate Cancer

Full Name
A Multi-Center, Prospective, Observational Study of Patients Being Treated With ORGOVYX (OPTYX).

Brief Description
The goal of this study is to generate real-world evidence about the safety and effectiveness of ORGOVYX in patients with prostate cancer in routine clinical care and the clinical course during treatment with and following cessation of ORGOVYX.

Sponsor
Sumitomo Pharma Switzerland GmbH Sponsored

ClinicalTrials.gov ID NCT05467176

View on Clinical Trials.gov